1996-2016. All Rights Reserved. Online Journal of Bioinformatics . You may not store these pages in any form except for your own personal use. All other usage or distribution is illegal under international copyright treaties. Permission to use any of these pages in any other way besides the  before mentioned must be gained in writing from the publisher. This article is exclusively copyrighted in its entirety to OJB publications. This article may be copied once but may not be, reproduced or  re-transmitted without the express permission of the editors. This journal satisfies the refereeing requirements (DEST) for the Higher Education Research Data Collection (Australia). Linking: To link to this page or any pages linking to this page you must link directly to this page only here rather than put up your own page.


 Online Journal of Bioinformatics  

  Volume 16 (2): 188-193, 2015.

Predicting evolution of coloured vision in mammals through systems biology.


1Shivani Sharma, 2Prashant Saxena


1Life Sciences, Institute of Applied Medicine and Research, Duhai, Ghaziabad, Uttar Pradesh, 2Bioinformatics, Sathyabama University, Chenna, Tamilnadu, India.




Sharma S, Saxena P., Predicting evolution of coloured vision in mammals through systems biology, Onl J Bioinform., 16 (2): 188-193, 2015. Since Darwin, genetic change was considered to be a direct indicator of variation in phenotype. More recently, epigenetic developmental processes have been proposed to affect phenotype, thus shifting focus from a linear genotype-phenotype map to a non-linear one. Long wave sensitive (LWS) opsin gene plays a role in trichromatic vision in humans and other mammals sensitive to the green-yellow range which differentiates between vivid colours more clearly. We describe evolution of colour vision in mammals through mutations of LWS gene leading to different phenotypes. LWS, MWS and SWS opsin genes contribute to the variable colour vision spectrum. Authors show why genotypic variation alone may not be responsible for genotypes in vision and that it is possible that epigenetic developmental events such as gene conversion, recombination errors or chimeric genes may have contributed to current genotypes.


Keywords: Evolution, Opsin gene, genotype, phenotype, colour vision.