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OJVRTM
Online
Journal of Veterinary Research©
Volume 17 (12): 638-644, 2013.
Effects of Zataria multiflora boiss
on experimental intestinal ischemia-reperfusion injury in male Wistar rats.
Naghmeh Ghasemkhani1(DVM), Omid Azari2*(DVM,
PhD), Reza Kheirandish3(DVM, PhD)
1School of
Veterinary Medicine, 2Department of Clinical Sciences, 3Department
of Pathology, School of Veterinary Medicine, Shahid Bahonar University of Kerman, Iran.
ABSTRACT
Ghasemkhani N, Azari O, Kheirandish R.,
Effects of Zataria multiflora boiss
on experimental intestinal ischemia-reperfusion injury in male Wistar rats, Onl J Vet Res., 17 (12):
638-644, 2013. The effects of
Zataria multiflora boiss
(ZM) oral extract on intestinal ischemia/reperfusion (I/R) injury in Male Wistar rats is described.
Rats were gavaged ZM 1 week before 45m
ischemia followed by 1h reperfusion (I/R) treatment. Groups of 5 rats each were
gavaged with 1 ml ZM 200ppm +I/R and 1 ml ZM 400ppm
+I/R. Controls were either gavaged 1 ml saline with
I/R or gavaged 1ml saline without I/R. At autopsy
jejunum tissue was excised and examined microscopically. I/R
controls showed severe mucosal damage whereas those given ZM appeared to have
less or no damage.
Key words:
Ischemia/reperfusion injury, Zataria multiflora,
Intestine, Rat
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