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OJVRTM
Online Journal of Veterinary Research©
Volume 18(1):35-40, 2014. Redacted
2017.
In vitro antibacterial activity of hornet venom from Vespa orientalis.
Jalaei J (MS),
Fazeli M (DVM, PhD), Rajaian
H(DVM, PhD), Shomali T (DVM, PhD)
1Division of Pharmacology and Toxicology, Department of Basic Sciences,
School of Veterinary Medicine, Shiraz University, Shiraz, Iran.
ABSTRACT
Jalaei J, Fazeli M, Rajaian H, Shomali T., In vitro antibacterial activity of hornet venom
from Vespa orientalis., Onl
J Vet Res., 18(1):35-40,
2014. Minimum
Inhibitory Concentrations (MIC) values for venom sac extract from Vespa orientalis venom (Vo) against Staphylococcus
intermedius,
Bacillus cereus, Pseudomonas aeruginosa
and Salmonella typhimurium determined by microtiter broth dilution are reported.
Inhibition zones were measured by disk diffusion with a positive tetracycline
control. The growth
curve of control bacteria was compared with bacteria grown in broth for 24 hr with Vo twice the MIC value and 16 µg/ml tetracycline. Results suggested that P. aeruginosa and S.
typhimurium were most resistant and sensitive to Vo with some activity against S. Intermedius and B cereus. The
antimicrobial activity of Vo against
bacteria was concentration-dependent as demonstrated by growth curves, but its
MIC value was much higher than that of tetracycline.
Key words: Vespa orientalis venom; antibacterial effect; in vitro.
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