2021-2032 All Rights Reserved. Online Journal of Veterinary Research . You may not store these pages in any form except for your own personal use. All other usage or distribution is illegal under international copyright treaties. Permission to use any of these pages in any other way besides the  before mentioned must be gained in writing from the publisher. This article is exclusively copyrighted in its entirety to OJB publications. This article may be copied once but may not be, reproduced or  re-transmitted without the express permission of the editors. This journal satisfies the refereeing requirements (DEST) for the Higher Education Research Data Collection (Australia). Linking:To link to this page or any pages linking to this page you must link directly to this page only here rather than put up your own page.


 Online Journal of Veterinary Research 

 Volume 25 (5): 341-350, 2021.

Epidemiological assessment of vaccine efficacy


GV Asokan, A Padmaraj and Johnsi Koruth.


Institute of veterinary preventive medicine, Ranipet, Tamil nadu-632 402 India




Asokan GV, Padmaraj A, Koruth J., Epidemiological assessment of vaccine efficacy, Onl J Vet Res., 25 (5): 341-350, 2021. Success of epidemiological programs against infectious diseases depends on effective prophylactic vaccines. Although efficacy and effectiveness are used interchangeably, effectiveness depends upon efficacy. Few methods are in use to assess the efficacy of the vaccine, a randomized double blind controlled trial is the least ambiguous method for evaluation. Observational designs for vaccine efficacy include cohort and case control and are useful when comparing vaccines with very large effectiveness. Modeling helps in designing vaccine. Serologic responses to antigens in combination vaccine differ from those obtained with separate administration of the components. Creation of a vaccine advisory and control authority is imminent.


Key words : Epidemiology, Vaccines, efficacy, effectiveness.