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OJVRTM
Online Journal of Veterinary Research©
(Including Medical and
Laboratory Research)
Established 1994
ISSN 1328-925X
Volume 29 (4): 219-224, 2025.
Leptospira
antibodies in aqueous humor of horses with or without uveitis.
Juliana Braga,
Camila Hamond, Gabriel Martins, Walter Lilenbaum
Department of
Microbiology, Universidade Federal Fluminense, Niteroi, Brazil
ABSTRACT
Braga J, Hamond C, Martins G, Lilenbaum W,
Leptospira antibodies in aqueous humor of horses with
or without uveitis, Onl J Vet Res., 29 (4): 219-224, 2025. We
assessed Leptospira
antibodies in serum and aqueous humor in 199 horses with or without uveitis. Sero-reactive animals were assessed by ophthalmological
examination. In horses with uveitis we evaluated antibodies and spirochetes in aqueous
humor and found 27.1% blood samples with high titers against Serovar Icterohaemorrhagiae.
Of 54 sero-reactive
animals, 38 had uveitis of which 31.6% of aqueous humor had titers < 25,
21.1% of 25, 50% of 50, and 13.2% ≥ 100, mostly against Icterohaemorrhagiae.
However, dark field microscopy did not reveal leptospires.
Results suggest equine uveitis may occur by cross-reaction of antibodies with
uveal antigens, not requiring L. Icterohaemorrhagiae.
Keywords: Leptospirosis,
Horses, Aqueous humor.