2021-2033. All Rights Reserved. Online Journal of Veterinary Research . You may not store these pages in any form except for your own personal use. All other usage or distribution is illegal under international copyright treaties. Permission to use any of these pages in any other way besides the before mentioned must be gained in writing from the publisher. This article is exclusively copyrighted in its entirety to OJVR. This article may be copied once but may not be, reproduced or re-transmitted without the express permission of the editors. This journal satisfies the refereeing requirements (DEST) for the Higher Education Research Data Collection (Australia). Linking:To link to this page or any pages linking to this page you must link directly to this page only here rather than put up your own page.


Online Journal of Veterinary Research

(Including Medical and Laboratory Research)

Established 1994
ISSN 1328-925X


Volume 26 (11): 795-801, 2022.

Effect of tilapia (Oreochromis Niloticus) skin powder on burn healing in rabbits.


Ali A. N. AL-Zaidi1*, Abd-AlhadiJaithom Marzok2, Hussien Kareem Ibraheim3, and Yassir AL-Zubaidi4


1,2,3Department(s) Clinical Science, Faculty of Veterinary Medicine, University of Kufa, Najaf, 4Pharmacology, College of Pharmacy, Albayan University, Baghdad, Iraq.




AL-Zaidi AAN, Marzok AA, Ibraheim HK, AL-Zubaidi Y., Effect of tilapia (Oreochromis Niloticus) skin powder on healing in rabbits, Onl J Vet Res., 26 (11): 795-801, 2022. We report effects of lyophilized tilapia fish skin on 400mm2 burn wound healing on 6 anesthetized adult male New Zealand rabbits over 28 days. At burn, and once daily rabbits were treated with 1/1 lyophilized tilapia fish skin powder with cold cream (1) or 10mg/g silver sulfadiazine cream (2). Controls were treated with cream (3). Wound reductions (%) were measured every 4 days for 28 days and overall time to healing determined. Compared with controls, in rabbits treated with skin powder, wounds retracted 56% more by day 4, 38% by day 16, and 18% by day 28 (P < 0.05). Epithelization was ~19% faster with tilapia powder and 8% with sulfadiazine (P < 0.05). By microscopy at 28 days, we observed that in controls, epidermis did not close wound due to vertical orientation of reticular collagen fibres whereas in rabbits treated with sulfadiazine where wound did close, displayed horizontal fascicular fibres. In rabbits treated with tilapia power we found re-epithelialization of all layers of epidermis by day 28.

Keyword: Tilapia skin, burn, healing, lyophilized, powder.