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Online Journal of Veterinary Research

(Including Medical and Laboratory Research)

Established 1994
ISSN 1328-925X


Volume 25 (8):593-599, 2021.

Erythrocyte oxidation markers in sheep infected by Theilera spp.


Hasan Baghshani1*, Gholam Reza Razmi2, Saeed Yaghfouri2, Amin Ahmadi Dezaki2

1Department of Basic Sciences and 2Department of Pathobiology, School of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, Iran


Baghshani H, Razmi GH, Yaghfouri S, Dezaki AA., Erythrocyte oxidation markers in sheep infected by Theilera spp., Onl J Vet Res., 25 (8):593-599, 2021. Authors report oxidative stress markers in sheep erythrocytes naturally infected with theileriosis. Thirty adult fat-tailed sheep were selected by clinical examination and positive peripheral Theileria spp blood smears. Controls consisted of 20 normal sheep without Theileria confirmed by blood smears. We determined erythrocyte haemolisate superoxide dismutase (SOD), glutathione peroxidase (GPx) and catalase (CAT), reduced glutathione (GSH) content and malondialdehyde (MDA). Compared with controls, erythrocyte SOD was lower (P < 0.05) ~-22% and GSH ~-33%, but MDA higher (P < 0.05) 90%, in sheep with Theileriosis. There were no differences in erythrocyte GPx or CAT. The results suggest that in sheep, Theileria spp boosts lipid peroxidation in erythrocytes.

Keywords: Theileria, Oxidative stress, Sheep, Endogenous antioxidants, Malondialdehyde.