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Online Journal of Veterinary Research©
(Including Medical and Laboratory Research)
Volume 25 (12):889-901, 2021.
Superoxide dismutase, glutathione peroxidase and thiobarbituric acid
in erythrocytes of ewes during breeding and pregnancy
M Mohebbi-Fania, A Mirzaeib, S Nazifib, M Tabandehc
aDepartment of Animal Health Management, bDepartment of Clinical Studies, School of Veterinary Medicine, Shiraz University, Shiraz 71345-1731, c Department of Basic Sciences, School of Veterinary Medicine, Shahid Chamran University, Ahvaz, Iran
Mohebbi-Fani M, Mirzaei A, Nazifi S, Tabandeh M., Superoxide dismutase, glutathione peroxidase and thiobarbituric acid in erythrocytes of ewes during breeding and pregnancy, Onl J Vet Res., 25 (12):889-901, 2021. We report anti-oxidant status in erythyrocytes of 3 to 5 year old 105 fat-tailed ewes during breeding and early-to-mid pregnancy under drought conditions. We measured erythrocyte superoxide dismutase (SOD), glutathione peroxidase (GPX) and thiobarbituric reactive substances (TBARS) at days 1, 7, 21 and 120 starting with introduction of rams. Ewes with ≥2.5 ng/ml progesterone at day 120 were considered pregnant (91%). By day 21 we found that plasma SOD declined -49% and GPX -81% (P < 0.05) but TBARS increased 71% (P < 0.05) maintaining trends to day 120. These results suggest that increased oxidation within reproductive tissues with protein deficiency may have reduced plasma SOD and GTX and boosted TBARS.
Key words: Superoxide dismutase, Glutathione peroxidase, Thiobarbituric reactive substances, Pregnancy, Ewes.