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OJVRTM
Online Journal of Veterinary Research©
Volume 18(10): 823-829, 2014. Redacted
2018.
Effect of
alcoholic extract of Tarantula cubensis on
wound healing in dogs
Mahdieh Rezaei1 DVSc,
Behrooz Fathi2 PhD, Kamran Sardari3
DVSc.
1Department(s) of Clinical Science,
Faculty of Veterinary Medicine, Shahid Bahonar University, Kerman, 2Basic Sciences, 3Clinical Sciences, Faculty
of Veterinary Medicine, Ferdowsi University of
Mashhad, Mashhad, Iran
ABSTRACT
Rezaei
M, Fathi B, Sardari K.,
Effect of alcoholic extract of Tarantula cubensis on
wound healing in dogs, Onl J Vet Res., 18(10): 823-829,
2014. We report effects of alcoholic extract of whole tarantula cubensis (Theranekron®),
on healing of skin wounds
in 5 dogs. Under general anesthesia, symmetrical
control and treated skin wounds (20×20 mm) were created on the dorsum of each
dog. Wounds were treated with 0.4ml tarantula extract subcutaneously (SC) and
0.4ml normal saline (control wound). Healing was monitored by digital images of
wounds taken at 0, 3, 6, 12, 15, 18 and 21 days. Areas of epithelialization and
granulation tissue were measured using Scion Image software allowing
percentages of wound contraction, epithelialization and healing to be
calculated. Epithelialization occurred by day 3 on treated wounds and at day 5
in control wounds. We found no significant
differences in percentage of wound contraction and epithelialization between test
and control wounds up to day 9 but by day 12 and 15 improved healing values may
have occurred in treated wounds.
Keywords: Theranekron, Tarantula
cubensis, Epithelialization, Wound contraction, Wound healing, Dog.
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