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Online Journal of Veterinary Research©
(Including Medical and Laboratory Research)
Volume 27 (3): 184-189, 2023.
Selection pressure of African swine fever virus attachment protein p12 gene.
You-Fang Chen1, Youhua Chen2
1School of Software, Harbin Normal University, Heilongjiang Province, China, 2Department of Renewable Resources, University of Alberta, Edmonton, T6G 2H1, Canada
Chen YF, Chen YH., Selection of African swine fever virus attachment protein p12 gene, Onl J Vet Res., 27 (3): 184-189, 2023. We describe selection pressure for attachment protein p12 gene of African swine fever virus. Phylogenetic relationship between seventeen p12 gene sequences shows conservative sequence similarity with very low nucleotide diversity (=0.0139). None of the models were different from nested ones suggesting that the attachment protein p12 gene is not subject to selection pressure due to high conservatism. We find no evidence of positive selection on the structural protein p12 gene, suggesting the gene has undergone purifying selection because the gene is vital for attachment and unlikely to undergo adaptive evolution.
KEYWORDS: natural selection, structural protein, adaptive evolution, Bayesian probability.