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OJVRTM

Online Journal of Veterinary Research©

Volume 5 (1): 161-171, 2001.

Adjuvancity of oil and vitamins A and E in infectious
bursal disease vaccine in chickens.

 Raghu TK, MVSca,  Nagaraja TR, MVScb, Anand Kumar P,  MVSc, Ph.Dc, Mishra SC, MVSc, Ph.Dd.

a Department of Animal Husbandry and Veterinary Services, Karnataka, India. b Animal Disease Monitoring and Surveillance, IAH and VB, Bangalore, Karnataka, India. cInstitute of Animal Health and Veterinary Biologicals, Hyderabad, Andra Pradesh, India. d Department Of Standardisation, Indian Veterinary Research Institute, India. Corresponding Address : Dr. T. K. Raghu. #2290, Harish Nilaya, @nd cross , Gandhi Nagar, Mandya _ 571 401, Karnataka, India.e-mail : raghu_tk_mandya@yahoo.com.

                                                                                          ABSTRACT

Raghu TK MVSc, Nagaraja TR MVSc, Kumar P MVSc PhD, Mishra SC MVSc Ph.D, Adjuvancity of oil and vitamins A and  E in infectious bursal disease vaccine in chickens. Online J Vet Res 5:161-171, 2001. Groups of 2 week old chicks were vaccinated subcutaneously with oil, vitamin A and vitamin E adjuvanted live infectious bursal disease (IBD) vaccines. IBD live-in-oil vaccine, vitamin A and E adjuvanted IBD live-in-oil vaccine and IBD live vaccine adjuvanted with vitamin A and E (injected adjacent to live vaccine), decreased mortality and enhanced antibody levels compared with IBD live vaccine alone; vitamin A and E may stimulate the interaction between immuno-competent cells at the site of inoculation.

KEY-WORDS :  Chicken ; live-in-oil vaccine ; Vitamin A ; Vitamin E

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