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OJVRTM
Online Journal of
Veterinary Research©
Volume 15 (3): 200-210, 2011. Redacted 2017.
Case Study: Feline spinal
cord gemistocytic astrocytoma
Elisângela Olegário da Silva1 DVM, Raquel Beneton Ferioli1, Kleber
Moren2 DVM PhD, Ana Paula F.R.L. Bracarense3 DVM PhD.
1Laboratory of Animal Pathology- 2Department of Veterinary
Clinics, 3Laboratory of Animal Pathology Universidade
Estadual de Londrina, Londrina-PR, Brazil.
ABSTRACT
Da Silva EO, Ferioli RB, Moreno K, Bracarense
AP., Case Study: Feline spinal cord gemistocytic
astrocytoma, Onl J Vet Res, 15 (3): 200-210, 2011. Primary spinal cord tumors are rare in cats. A six-year-old, intact male
Siamese cat had a history of progressive hemiparesia,
muscle atrophy in the right thoracic limb and regional pain. Neurological exam
revealed increased reflexes, hyperesthesia and propioceptive
deficit in the right thoracic limb. Medical therapy was initiated, but
neurological signs were progressive and severe, affecting the pelvic limbs. The
owner opted for euthanasia. Gross exam showed a swollen area in the C6 region
of the spinal cord. Histopathological examination showed diffuse proliferation
of large cells with abundant eosinophilic cytoplasm and eccentrically located
large nuclei with prominent 8positive staining for S100, vimentin and GFAP (glial
fibrillar acid protein) and negative staining for
macrophage antigens (lysozyme and LN-5). Based on histopathological and immunohistochemical features, a diagnosis of gemistocytic astrocytoma was made.
Keywords: spinal cord, tumor, cat.
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