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OJVRTM

Online Journal of Veterinary Research©

 

Volume 18(8): 668-674, 2014.


 Characterization of class 1 integrons and antibiotic resistance in human and poultry Salmonella enterica isolates. 

 

Ladan Mansouri Najand1 (DVM, PhD), Parisa Amini2 (DVM), Masoud Sami1 (DVM, PhD), Nasrin Askari3 (DVM), Kumars Amini4 (DVM, PhD)

 

1Department of Food Hygiene and Public Health, 2,3Faculty of Veterinary Medicine, Shahid Bahonar University of Kerman,  4Department of Microbiology, Faculty of Agriculture, Islamic Azad University, Saveh Branch, Saveh, Iran

 

ABSTRACT

 

Mansouri Najand L, Amini P, Sami M, Askari N, Amini K., Characterization of class 1 integrons and antibiotic resistance in human and poultry Salmonella enterica isolates, Onl J Vet Res., 18(8): 668-674,  2014. Class 1 integrons were detected in 42 of 60 Salmonella isolates. Serotypes found in poultry and humans were  S. Typhimurium (14 and 9) and S. Enteritidis (8 and 11), respectively.  Most integron positive isolates were multi-drug resistant (MDR) and showed resistance to 2 or more antibiotic families. Antibiograms of human isolates of salmonella showed a maximum range of 93% resistance against erythromycin but a maximum range of sensitivity of 90% against ciprofloxacin. In both serovars of salmonella isolated from poultry the maximum range of resistance was against cefazolin (100%) and maximum range of sensitivity against ciprofloxacin (67%). Findings suggest an association between integron carriage and reduced susceptibility to some first-line antibiotics prescribed in human and animal salmonellosis.

 

Key word: Salmonella Enteritidis, Salmonella Typhimurium, multi-drug resistant, class I integrons.


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