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OJVRTM
Online Journal of
Veterinary Research©
Effect of topical Rosa
damascene mill gel on hydroxyproline in dermis of mature male Sprague Dawley
rats.
Nasser Vajdi1*, Aboutorab
Tabatabaei-Naeini2, Ahmad Oryan3, Fatemeh
Abbasi-Teshnizi4
1,2Department(s) of Surgery, 3Pathology, 4Sciences,
School of Veterinary Medicine, Shiraz University, Shiraz,
Iran.
ABSTRACT
Vajdi N, Tabatabaei-Naeini A, Oryan A, Abbasi-Teshnizi F.,
Effect of topical Rosa damascene mill gel on hydroxyproline
in dermis of mature male Sprague Dawley rats, Onl J
Vet Res., 20(10):652-659, 2016.
Effect of Rosa damascene mill
gel on hydroxyproline content in rat dermis is
described. Four groups of 10 mature male white Sprague-Dawley male rats each
were used as controls and
treatments. Following routine surgical preparation, a 1cm circle of dorsal cervical
skin was excised from each rodent. Treated rats were applied 5% and 10% R. damascene mill gel whereas placebo controls, a daily topical base gel, and treated controls, oxytetracycline spray for 7d. Ten and 20 days later rats were
euthanized and biopsies were taken from the site for hydroxyproline
content. There was no statistical difference in hydroxyproline
content of skin samples between any group.
Keywords-Rosa damascene mill gel, Hydroxyproline,
Skin, Rat.
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