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Online Journal of Veterinary Research©
Volume 22 (1):15-24, 2018.
Effect of Midazolam-Ketamine on renal artery and aorta resistive and pulsatility indices in cats by pulse wave doppler ultrasonography.
Niloufar Ghahari1, Yasamin Vali DVM PhD*2, Shahram Jamshidi DVM PhD3, Keyvan Keramati DVM PhD4, Saeideh Naeimi DVM PhD5
1,4,5Faculty of Veterinary Medicine, University of Semnan, Semnan, 2Departments of Radiology and 3Internal Medicine, Faculty of Veterinary Medicine, University of Tehran, Iran. *Corresponding author:Yasamin Vali
Ghahari N, Vali Y, Jamshidi S, Molazem M, Keramati K., Effect of Midazolam-Ketamine on renal artery and aorta resistive and pulsatility indices in cats by pulse wave doppler ultrasonography, Onl J Vet Res., 22 (1):15-24, 2018. Sedation may be necessary with aggressive cats during ultrasound examination leading to misinterpretation of vascular changes in renal failure. We report effect of intramuscular injection of midazolam-ketamine on renal artery and abdominal aorta resistivity (RI) and pulsatility (PI) determined by wave Doppler ultrasonography in normal adult domestic shorthair cats. Ten cats were sedated and 10 controls were not. We found no statistical difference between right and left kidney's RI and PI values. In sedated cats renal artery RI was 0.72 ± 0.07 and PI 1.29 ± 0.32, but in controls 0.55 ± 0.05 and 0.70 ± 0.26 (P < 0.001). Abdominal aortic RI was 0.77 ± 0.07 and PI 2.13 ± 0.63 whereas in controls were 0.71 ± 0.04 and 1.34 ± 0.61 (P=0.013). We find that intramuscular administration of midazolam-ketamine affects pulsed wave Doppler ultrasonographic renal and aortic RI and PI results in cats.
Key words: feline, Doppler ultrasonography, resistive index, pulsatility index, ketamine-midazolam.