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OJVR
Online Journal of Veterinary Research©
Volume 22 (1):15-24, 2018.
Effect of Midazolam-Ketamine on renal
artery and aorta resistive and pulsatility indices in
cats by pulse wave doppler
ultrasonography.
Niloufar Ghahari1, Yasamin Vali DVM
PhD*2, Shahram Jamshidi
DVM PhD3, Keyvan Keramati
DVM PhD4, Saeideh Naeimi
DVM PhD5
1,4,5Faculty of Veterinary Medicine, University of Semnan, Semnan, 2Departments
of Radiology and 3Internal Medicine, Faculty of Veterinary Medicine,
University of Tehran, Iran. *Corresponding author:Yasamin Vali
ABSTRACT
Ghahari N, Vali Y, Jamshidi S, Molazem M, Keramati K., Effect of
Midazolam-Ketamine on renal artery and aorta resistive and pulsatility
indices in cats by pulse wave doppler
ultrasonography, Onl J Vet Res., 22 (1):15-24, 2018. Sedation may be necessary with aggressive cats during
ultrasound examination leading to misinterpretation of vascular changes in
renal failure. We report effect of intramuscular injection of
midazolam-ketamine on renal artery and abdominal aorta resistivity (RI) and pulsatility (PI) determined by wave Doppler ultrasonography
in normal adult domestic shorthair cats. Ten cats were sedated and 10
controls were not. We found no statistical difference between right and left
kidney's RI and PI values. In sedated cats renal artery RI was 0.72 ± 0.07 and
PI 1.29 ± 0.32, but in controls 0.55 ± 0.05 and 0.70 ± 0.26 (P < 0.001).
Abdominal aortic RI was 0.77 ± 0.07 and PI 2.13 ± 0.63 whereas in controls were
0.71 ± 0.04 and 1.34 ± 0.61 (P=0.013). We find that intramuscular
administration of midazolam-ketamine affects pulsed wave Doppler ultrasonographic renal and aortic RI and PI results in
cats.
Key words: feline, Doppler ultrasonography, resistive index, pulsatility index, ketamine-midazolam.
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