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Online Journal of Veterinary Research


Volume 24(10): 589-599, 2020

Effect of Pistacia atlantica oil on oxidation and wound healing in Sprague Dawley male rats.


A. Tabatabaii Naeini1, A. R. Hamidi1, N. Tanideh2 & S. Nazifi1


1Department of Clinical Studies, School of Veterinary Medicine, Shiraz University; 2Department of Stem Cell and Transgenic Technology Research Center; Pharmacology Department, Shiraz University of Medical Sciences, Shiraz, Iran.




Naeini AT, Hamidi AR, Tanideh N, Nazifi S., Effect of Pistacia atlantica oil on oxidation and wound healing in Sprague Dawley male rats, Onl J Vet Res., 24(10): 589-596, 2020. Bene (Pistacia atlantica) hull oil (BHO), contains stable anti-oxidative vegetable oils. Antioxidant activity of BHO on superoxide dismutase, catalase, glutathione peroxidase and lipid peroxidation in anaesthetized rats with 2X2 cutaneous vertebrae experimental wound is reported. Groups of 25 rats each were treated with base gel, 5% or 10% BHO gel. Controls consisted of wounded but untreated rodents. Blood was taken at 3, 7, 10, 14 and 21 days post-injury. Results suggested that activities of the main erythrocyte antioxidant enzymes began to decline 10 days after wound creation in control and base gel groups but increased progressively in those given BHO.


Key words: Pistacia atlantica, bene hull oil, enzymatic antioxidants, lipid peroxidation, rat.