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OJVRTM
Online Journal of Veterinary Research©
Volume
18(6): 456-467, 2014. Redacted 2017.
Effect of
Persian sage (Salvia rhytidia Benth) on heart and kidney tissue and serum biochemistry
during liver ischemia-reperfusion in rats.
Mohammad M
Oloumi (DVM, DVSc)1, Amin Derakhshanfar
(DVM, PhD)2, Arash Ashraf (DVM)1.
1Department
of Clinical Science, Faculty of Veterinary Medicine, Shahid
Bahonar University of Kerman, 2Center of Comparative & Experimental Medicine, Basic Sciences in
Infection Diseases Research Center, Shiraz University of Medical Sciences, Iran
ABSTRACT
Oloumi MM, Derakhshanfar
A, Ashraf A., Effect of Persian sage (Salvia rhytidia
Benth) on heart and kidney tissue and serum
biochemistry during liver ischemia-reperfusion in rats, Onl
J Vet Res., 18(6): 456-467, 2014. Effect of Persian sage (PS) essential oil on kidney
and heart injuries following liver ischemia-reperfusion (IR) is described. Four
groups of
6 rats were given PS and subjected to 1 or 24 hours IR and then sacrificed. Ischemia was induced surgically in the left lateral and
median lobes of the liver and rats were sacrificed immediately after
reperfusion. The rodents received oral 0.2 ml/kg of 0.02% PS essential oil at different times. Other groups (4) were used as saline
and reperfusion ischemia controls. Tissue and blood samples were taken for
histopathological, and serum BUN, Cr, LDH, and CK values. Microscopy and
biochemical results suggested a protective effect of PS on kidneys and heart
tissue.
Key Words: Persian sage, Salvia rhytidia,
Liver ischemia-reperfusion, Heart, Kidney, Multiple organ injuries.
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