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Online Journal of Veterinary Research©
(Including Medical and Laboratory Research)
Volume 25 (7):465-472, 2021.
Effect of papyrus protein supplement on lead and antioxidants in blood of female rabbits.
Khayreia Kazzum Habeeb1, Bahaa Fakhri Hussein*2, Ahmed Adeeb Mohamed3 Muhammed Mizher Radhi4
1Department(s) of Surgery, 2Anatomy & Histology, , Faculty of Veterinary Medicine, University of Baghdad, Baghdad, Iraq, 3Al-Muthanna University, College of Pharmacy , 4Radiology, Health and Medical Technology College-Baghdad, Iraq.
Habeeb KK, Hussein BF, Mohamed AA, Radhi MM., Antioxidant effect of papyrus protein on lead ion toxicity in female rabbits, Onl J Vet Res., 25 (7):465-472, 2021. We describe effect of papyrus protein supplement on plasma lead and antioxidants by voltametry in young rabbits. Groups of 5 rabbits each were injected intraperitoneally 1mg/kg lead acetate 56 days. Controls were injected 1ml saline intraperitoneally. Compared with lead levels at day 7, lead in blood accumulated 46% by day 14, 68% at day 35 days and 79% (P <0.0001) by day 56. In contrast in those given papyrus supplement with lead we found 6 to 27 fold or 84 to 96% less lead acetate in blood throughout (P < 0.0001) equivalent to a decline from 12.138 to 0.379 mg/l lead acetate in rabbits gavaged papyrus supplement. Papyrus protein compound reduced (P<0.05) current oxidation peak of lead ions from 16.8 µA to 2.9 µA or in average ~83% over the 8 week period. The findings suggest that papyrus protein may bind strongly to lead acetate.
Keywords: Lead ions, Blood Medium, Cyclic Voltammetry, GCE, papyrus protein, Rabbit.