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OJBTM
Online
Journal of Bioinformatics©
Volume 8 (1) : 41-44, 2007
Database and interactome
map of genes involved in oral cancer
1Bioinformatics centre (BTIS Sub-DIC), Advanced Centre for Treatment
Research and Education in Cancer, Tata Memorial
Centre, Kharghar, Navi
Mumbai, India
ABSTRACT
Gadewal NS, Zingde SM., Database and interactome
map of genes involved in oral cancer, Online J Bioinformatics, 8 (1) 41-44,
2007. In
the post genomic era, efforts to understand oral cancer are aimed at obtaining
genomic and proteomic profiles for cancer management. The database in this
report information and external links for
242 genes involved in oral cancer, interactions between them, their role in the
biology of oral cancer, along with clinical relevance. Each gene gives detailed
information on aliases, function, chromosomal location, mutations and SNPs, mRNA expression, protein information, pathways
involved and interacting proteins, expression of genes in different tissues,
and clinical correlates. For querying the database a search engine retrieves
the genes by symbol, name, chromosomal location, gains and losses of
chromosomal regions and molecular weight. Interactome
maps have been generated for the genes that are categorized into important
biological processes and molecular functions based on Gene-Ontology.
KEYWORDS: Oral cancer, Database, Interactome
map