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Online Journal of Veterinary Research©
Volume 25 (1); 22-27, 2021.
Effect of obesity on inflammatory white adipose tissue cytokines and chemokines.
Wafaa Ayad Abdulqader
College of Science, Al-Muthanna University, Iraq.
Abdulqader WA., Effect of obesity on inflammatory white adipose tissue cytokines and chemokines, Onl J Vet Res., 25 (1);22-27, 2021. Obesity is characterized by low-grade inflammation with secretion of inflammatory cytokines or chemokines TNF-α, IL-6, IL-1_ᵦ, Leptin, adiponectin, resistin, acylation-stimulating protein, SAA3, ᵅ_1 acid glycoprotein, pentraxin-3, IL-1 receptor antagonist and macrophage migration inhibitor factor. Author reviews changes in adipose resident immune (ARI) cytokines and chemokines from macrophages, CD4, CD8, T cells, endothelial cells, fibroblasts and multipotent mesenchymal cells in obesity. In particular the roles of interleukins 1, 6 and 8, TNF-α, RANTES and monocyte chemoattractant protein-1 in obesity are discussed.
Key words: Obesity, adipose cytokines, chemokines.