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Online Journal of Veterinary Research©

(Including Medical and Laboratory Research)

Established 1994

ISSN 1328-925X

 

Volume 29 (1): 25-35, 2025.

Substance P, calcitonin, gene-related peptide, galanin and calcium binding proteins

in myenteric plexuses of goat small intestine.

 

In Koo Hwang DVM MS, Heungshik S Lee DVM PhD, Young Sam Nam DVM BS, Choong Hyun Lee DVM MS,

Yeo Sung Yoon DVM PhD, Tae-Cheon Kang DVM PhD, Moo Ho Won DVM PhD, In Se Lee DVM PhD.

 

Department (s) of Anatomy, College of Veterinary Medicine and School of Agricultural Biotechnology, Seoul National University, Suwon, College of Medicine, Hallym University. Chunchon, Kangwon-Do, College of Veterinary Medicine and School of Agricultural Biotechnology, Seoul National University, Suwon, South Korea.

 

ABSTRACT

 

Hwang IK,  Lee HS, Nam YS, Lee CH, Yoon YS, Kang TC, Won MH, Lee IS., Substance P, calcitonin, gene-related peptide, galanin and calcium binding proteins in myenteric plexuses of goat small intestine, Onl J Vet Res., 29 (1): 25-35, 2025. Immuno-histochemical and double immuno-fluorescense was used to localize calbindin D-28k (CB), calretinin (CR), parvalbumin (PA), substance P (SP), calcitonin gene-related peptide (CGRP) and galanin (GAL) in the goat small intestine. Localization of CB with SP, CGRP or GAL in the myenteric and submucosal plexuses suggests that CB may serve a neuromodulatory role for SP-, CGRP- and GAL-immuno-reactive neurons in intestinal wall motility. Distributions of CB, CR and SP of the goat small intestine differ from guinea-pig and pig. This difference may be relevant to morphological characteristics.

 

Key Words: Immunochemistry substance P, calcitonin, gene related peptide.

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