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Online Journal of
Veterinary Research
Volume 1:7-17, 2002. Redacted
2018.
Immunohistochemical localization of
substance P, calcitonin gene-related
peptide, galanin and calcium binding proteins
in myenteric and
submucosal plexuses of goat small intestine
Hwang IK, Lee HS, Nam YS, Lee CH, Yoon YS, Kang TC, Won MH, Lee IS
Department
of Anatomy, College of Veterinary Medicine and School of Agricultural
Biotechnology, Seoul National University, Suwon, Kyunggi-Do,
441-744, South Korea.*Department of Anatomy, College of Medicine, Hallym University. Chunchon, Kangwon-Do, 200-702, South Korea.+Corresponding
Author, Dr. In Se Lee, Department of Anatomy, College of Veterinary Medicine
and School of Agricultural Biotechnology, Seoul National University, Suwon, Kyunggi-Do, 441-744, South Korea, TEL: +82-31-290-2743,
FAX: +82-31-290-2717, E-mail: inselee@snu.ac.kr
ABSTRACT
Hwang IK, Lee HS, Nam YS, Lee CH, Yoon YS, Kang TC,
Won MH, Lee IS, Immunohistochemical localization of substance P, calcitonin
gene-related peptide, galanin and calcium binding proteins in myenteric and
submucosal plexuses of goat small intestine Onl J Vet
Res., 1:7-17, 2002. Immunohistochemical
and double immunofluorescence was used to identify the localization of calbindin D-28k (CB), calretinin
(CR), parvalbumin (PA), substance P (SP), calcitonin
gene-related peptide (CGRP) and galanin (GAL) in goat
small intestine. Localization of CB with SP, CGRP or GAL in the myenteric and
submucosal plexuses suggests that CB may serve a neuromodulatory
role for SP-, CGRP-, and GAL-immunoreactive neurons
in intestinal wall motility. Distributions of CB, CR and SP of the goat small
intestine differ from guinea-pig and the pig. This difference may be relevant
to morphological characteristics.
Key Words: calcitonin gene-related peptide, galanin,
calcium binding proteins, myenteric and submucosal plexuses, goat, small
intestine
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