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Online Journal of Veterinary Research©

 

Volume 9 (2) :79-82, 2005. Redacted 2018.


Genotoxity of nitroxynil and moxydectin in sheep

 

Adam ML1, Torres RA2, Sponchiado G1, Requião L1, Oms PA1

 

1Laboratório de Citogenética; Núcleo de Ciências Biológicas e da Saúde; Centro Universitário Positivo, UnicenP. 2Laboratório de Genômica Evolutiva e Ambiental, Departamento de Zoologia, UFPR. Centro Politécnico; Jardim das Américas; Curitiba, PR, Brazil. CEP 81531-990. †Author for correspondence: ratorres@ufpr.br

 

ABSTRACT

 

Adam ML, Torres RA, Sponchiado G, Requião L, Oms PA Genotoxity of nitroxynil and moxydectin in sheep, Onl J Vet Res., 9 (2) :79-82, 2005. Micronuclei assays were used to determine the genotoxicity of nitroxynil (Devoxin®) and moxidectin (Cydectin®) given 1ml/50kg and 1ml/25kg at 45 and 105 days of age, respectively, in 2 groups of 5 Suffolk sheep. There was no significant difference between treated and control (untreated newborn) animals in the frequency of micronucleated cells. 

 

KEY WORDS: micronucleus assays, genoxicity, anthelmintics, sheep.


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