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Online Journal of Veterinary Research©

(Including Medical and Laboratory Research)

Established 1994

ISSN 1328-925X


Volume 28(3): 146-155, 2024.

Antibiotic probiotic resistance by Staphylococcus aureus isolated from surgical site patients.

Sherein I Abd El-Moez, Sohad M Dorgham, Eman Abd El-Aziz.

Department of Microbiology and Immunology, National Research Center, Giza, Egypt.




El-Moez SI, Dorgham SM, El-Aziz EA., Antibiotic probiotic resistance by Staphylococcus aureus isolated from surgical site patients, Onl J Vet Res., 28(3): 146-155, 2024. We report methicillin resistant Staphylococcus aureus (MRSA) from hospital patientís pus, sputum and blood samples from surgical sites determined by mec-A gene quantitative-PCR. We then tested the isolates against various antibiotics and probiotic lactobacilli from colostrum, milk and fecal samples of mares, cows or goats. Strains were plated onto Mueller Hinton agar plates. We found  mec-A gene in 6 of 7 samples. Cefobid and claforan and probiotics B. subtilus, L. acidophilus from colostrum of mares and L. acidophilus from goat colostrum were most effective against MRSA. However, L. acidophilus from Buffalo-cow milk showed no activity. We find that mec-A gene was involved in all MRSA patients with severe skin infections. 


Keywords: MRSA; Quantitative-PCR; mec-A gene; Antibiotic sensitivity; Human; Probiotics.