©2021-2032 All Rights Reserved. Online Journal of Veterinary Research. You may not store these pages in any form except for your own personal use. All other usage or distribution is illegal under International copyright treaties. Permission to use any of these pages in any other way besides the before mentioned must be gained in writing from the publisher. This article is exclusively copyrighted in its entirety to OJVR publications. This article may be copied once but may not be, reproduced or re-transmitted without the express permission of the editor.
Online Journal of Veterinary Research©
(Including Medical and Laboratory Research)
Volume 25 (10):684-694, 2021.
Effects of methamphetamine on KI-67, PPARα, PPARγ and Bax genes on
human SH-SY5Y cell proliferation, differentiation and apoptosis.
Marzieh Zamani-Pereshkaft1, Davood Mehrabani2,3,4*, Bahareh Borzou5, Shahrokh Zare2, Iman Jamhiri2
1Department of Genetics, Yazd Science and Art University, Yazd, 2Stem Cell Technology Research Center, 3Burn and Wound Healing Research Center, 4Comparative and Experimental Medicine Center, Shiraz University of Medical Sciences, 5Department of Biochemistry, Shiraz Branch, Islamic Azad University, Shiraz, Iran.
Zamani-Pereshkaft M, Mehrabani D, Borzou B, Zare S, Jamhiri I., Effects of Methamphetamine on KI-67,
PPARα, PPARγ and Bax
genes on human SH-SY5Y cell proliferation, differentiation and apoptosis, Onl J Vet Res., (10):684-694, 2021. Methamphetamine
is a powerful stimulant of the central nervous system. We describe effect of the
drug on cell viability, proliferation, differentiation and apoptosis in human
SH-SY5Y cells. Succinate dehydrogenase activity (MTT
assay) was used to determine neurotoxicity and RT-
Key words: Methamphetamine, Neurotoxicity, SH-SY5Y cells, Proliferation, Differentiation, Apoptosis.