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OJVRTM
Online Journal of
Veterinary Research©
Volume 7:10-16, 2003. Redacted 2018.
Effect of intravenous Medetomidine-Buprenorphine
on canine tear flow
Soontornvipart K1,2,
Rauser P2, Kecová
H2, Lexmaulová L2.
1Department of Surgery, Faculty of Veterinary
Medicine, Chulalongkorn University, Bangkok,
Thailand, 2Department of Small Animal, University of Veterinary and
Pharmaceutical Sciences, Brno, Czech Republic.
ABSTRACT
Soontornvipart K., P. Raušer,
H. Kecová, L. Lexmaulová:
Effect of intravenous medetomidine-buprenorphine on
canine tear flow, Onl J Vet Res., 7:10-16, 2003. Tear flow rate was measured in 28 healthy dogs and 5 dogs with Dry-Eye
Syndrome (DES) using the Shirmer Tear Test (STT). STT
was measured before, and 10 and 30 minutes after anesthetic IV pre-medication
with 20 µg/kg medetomidine and 10 µg/kg
buprenorphine. Untreated healthy dogs had a mean STT of 16.9 + 1.08
mm/min before treatment, 1.7+ 0.94 mm/min at 10 min, and 0 mm/min at 30
min, after treatment. Animals with DES had mean STT of 6.4 + 0.18 mm/min
before treatment and 0 mm/min by 10 min after treament.
Age, breed, sex and body weight did not affect STT values. The results suggest
that tear flow should be monitored during pre-anaesthesia
to prevent corneal damage; The cornea should be
protected by administration of artificial tear preparations.
KEY-WORDS: Tear flow; pre-anaesthesis, medetomidine-buprenorphine;
dog