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Online Journal of Veterinary Research ©
(Including Medical and Laboratory Research)
Volume 27 (10): 566-569, 2023.
Effect of meloxicam on antibiotic treatment of mastitis in cattle and buffalo
Justin William B, Johnson Rajeswar J.
Department of Surgery, Madras Veterinary College, Chennai, India.
William JB, Rajeswar JJ., Effect of meloxicam on antibiotic treatment for mastitis in cattle and buffalo, Onl J Vet Res., 27 (10): 566-569, 2023. Authors report clinical efficacy of meloxicam with or without antibiotic for therapy of mastitis in 20 cattle and buffalo. Ten healthy controls were not treated. One group of 7 cows and 3 buffalo with clinical mastitis were given 0.5mg/kg antibiotic intramuscularly, and another 8 cows and 2 buffalo 0.5mg/kg antibiotic with 0.5mg/kg meloxicam intramuscularly. Surface temperature of injection site was recorded by thermo sensitive indicator strip before injection, 2 and 24 hours after. Rectal temperature, heart rate, respiratory rate, hematology, serum proteins and blood glucose and California mastitis tests were determined at days 1, 2, 3, 7, 15 and 30. Injections did not induce inflammation or temperature. Compared with cows given only antibiotics, meloxicam maintained rectal temperatures, respiratory rates ~3% and California mastitis test values 32-45% lower, whereas hemoglobin ~4%, red cells 5-17% and glucose 5% higher (P < 0.05). Our findings suggest meloxicam boosts effect of antibiotics in cows with mastitis.
Key words: Meloxicam – Efficacy – Mastitis.