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OJVRTM

Online Journal of Veterinary Research©

 Volume 24(9): 554-557, 2020.


Effect of melatonin with or without progesterone implants on serum reproduction hormones and anestrus in lactating buffalo.

 

Talib Musa Al-Hamedawi and Saad Akram Hatif.

 

College of Veterinary Medicine, University of Baghdad, Baghdad-Iraq.

 

ABSTRACT

 

Al-Hamedawi TM, Hatif SA., Effect of melatonin with or without progesterone implants on serum reproduction hormones and anestrus in lactating buffalo, Onl J Vet Res., 24(9): 554-557, 2020. We describe effect of melatonin with or without progesterone controlled internal drug release  devices (CIDR) implant on serum estrogen, progesterone, prolactin, melatonin and anestrus in lactating buffalos. We used 3 groups of ten 3 to 6 year old buffaloes each with ovarian inactivity at 60-90 days postpartum. The animals were given five 90mg melatonin implants subcutaneously over 30 days with or without 1.38gm medroxy acetate progesterone at day 20 for 10 days.  Controls were not treated. Jugular blood was taken for serum estrogen, progesterone, prolactin and melatonin at days 0, 15 and 37 of treatment determined by ELISA. In buffalo given only melatonin, serum estrogen increased (P < 0.05) ~69% by day 37 but in those also given progesterone, estrogen increased ~39% but by day 15, and ~72% by day 30. We found similar results with serum progesterone and melatonin but no effect on serum prolactin levels. These finding suggest that melatonin with or without progesterone CIDR implants may improve reproductive outcomes in lactating anestrus buffalos.

 

Key words: Buffaloes, Ovarian inactivity, Melatonin, CIDR, Prolactin.


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