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OJVRTM
Online Journal of
Veterinary Research©
Volume 23 (9):890-897, 2019.
Effects of Silymarin (silybum
marianum) supplement on blood and liver markers
in broilers fed mycotoxin.
Abbas Fadhil Oleiwi, Mushtaq Talib Abdulwahid.
Dept. Public Health, College of Veterinary
Medicine, University of Baghdad.
ABSTRACT
Oleiwi AF, Abdulwahid
MT., Effects of Silymarin (silybum marianum) supplement on blood and
liver markers in broilers fed mycotoxin, Onl J Vet
Res., 23 (9):890-897, 2019. We report effect of silymarin (Silybum
Marianum) supplement on blood
biochemistry and liver morphology in Ross 308 broiler chickens fed mycotoxins. Four groups
of six 1-day old chicks were fed basal diet with or without
mycotoxins or 0.5% Silymarin/kg feed. After 35 days,
blood samples were taken for blood biochemistry and liver histology. Compared
with controls, in broilers fed basal diet with mycotoxin, serum protein
declined ~41% AST increased 16% and ALT 37% whereas in those supplemented Silymarion protein increased 44%, AST increased 12* and ALT
32%. In those fed basal diet with sylimarin protein
increased 54% (P < 0.01). In those given mycotoxin, we observed hepatic
mononuclear and Kuffer cell infiltrations, granulomas
and cellular atrophy with fibrosis or portal
vein occlusion with thrombi infiltrated by leucocytes.
Keywords: mycotoxins, Liver functions tests, Silymarin,
milk thistle, histology. Raw data provided.
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