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Online Journal of Veterinary Research


Volume 23 (9):890-897, 2019.

Effects of Silymarin (silybum marianum) supplement on blood and liver markers in broilers fed mycotoxin.


Abbas Fadhil Oleiwi, Mushtaq Talib Abdulwahid.


Dept. Public Health, College of Veterinary Medicine, University of Baghdad.




Oleiwi AF, Abdulwahid MT., Effects of Silymarin (silybum marianum) supplement on blood and liver markers in broilers fed mycotoxin, Onl J Vet Res., 23 (9):890-897, 2019. We report effect of silymarin (Silybum Marianum) supplement on blood biochemistry and liver morphology in Ross 308 broiler chickens fed mycotoxins. Four groups of six 1-day old chicks were fed basal diet with or without mycotoxins or 0.5% Silymarin/kg feed. After 35 days, blood samples were taken for blood biochemistry and liver histology. Compared with controls, in broilers fed basal diet with mycotoxin, serum protein declined ~41% AST increased 16% and ALT 37% whereas in those supplemented Silymarion protein increased 44%, AST increased 12* and ALT 32%. In those fed basal diet with sylimarin protein increased 54% (P < 0.01). In those given mycotoxin, we observed hepatic mononuclear and Kuffer cell infiltrations, granulomas and cellular atrophy with fibrosis or portal vein occlusion with thrombi infiltrated by leucocytes.


Keywords: mycotoxins, Liver functions tests, Silymarin, milk thistle, histology. Raw data provided.