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Online Journal of Veterinary Research

Volume 25 (4): 272-280, 2021

Magnesium sulfate nano-molecular contrast media for cardiac and kidney computed tomography.


Hiba Karim Abd1, Muhammed Mizher Radhi2


1Radiological Techniques Department, Health and Medical Technology College-Baghdad, 2Middle Technical University (MTU), Iraq.




Karim Abd H, Radhi MM, Magnesium sulfate nano-molecular contrast media for cardiac and kidney computed tomography. Onl J Vet Res., 25 (4): 272-280, 2021. The most common contrast medium for computed tomography (CT-Scan) examinations is iodine solution. However, iodine compounds can induce allergy and/or kidney failure. We describe production and tomography for magnesium sulfate nanoparticle solution alternative contrast agent. Compared with rabbits given 1 to 5ml iodine HU values were comparable with those given only 0.5 to 2.5ml nanoparticles. Magnesium sulfate nanoparticles concentrations were 15mg/ml compared with 350mg/ml iodine or 23 times greater. At 2ml nanoparticles contrast was higher (108.2) than 4ml iodine (94). We did not observe any adverse symptoms in rabbits treated with iodine or nanoparticles. We surmise that at low doses (0.5ml to 2ml) magnesium, nanoparticles may have application as contrast agent for CT scans.


Keywords: Magnesium sulphate, Nano solution, CT-scan, iodine contrast medium, Hounsfield unit, heart.