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OJVRTM

Online Journal of Veterinary Research©

 

Volume 26 (8): 587-592, 2022.


Effect of ocular lipid layer on aqueous layer in brachycephalic dogs evaluated

by interferometry, meibomian gland and Schirmer tear tests

 

Paulo Henrique Sampaio da Silva* (DVM), Layla Karolaynne Souza Cruz (DVM),

Brendha Mendes Ferreira (DVM), Mário Sérgio Almeida Falcão  (DVM, PhD)

 

¹Veterinary Center of Vision, Cond. San Diego, lt 385, Jardim Botanico, Brasília, Brazil.

*Corresponding author: phss96silva@gmail.com

 

ABSTRACT

 

Silva PHS, Cruz LKS, Ferreira BM, Falcão MSA Effect of ocular lipid layer on aqueous layer in brachycephalic dogs evaluated by interferometry, meibomian gland and Schirmer tear tests,  Onl  J Vet Res., 26 (8): 587-592, 2022. Status of aqueous pre-corneal layer can be evaluated by Schirmer Tear Test-1. However, the lipid layer which is thought to prevent evaporation and loss of fluid from the aqueous layer can only be tested indirectly. We report effect of lipid layer on ocular aqueous layer in 18 brachycephalic dogs (36 eyes) by eye surface interferometry, Schirmer tear tests and loss of meibobian gland area. Dogs were first subjected to ophthalmic examination, interferometry patterns and meibography by ocular surface analysis. We found significant (p < 0.05) difference for Schirmer tear tests by interferometry of eye surface between dogs measuring 15-30nm which secreted 18.33 ± 5.61mm/min (CI 95%, 14.77 : 21.90) and 61-100nm yielding 24.67 ± 4.67mm/min (CI 95% 21.69 : 27.64). Loss of Meibomian gland area was associated with lower interferometry grades (n=20). 22 eyes presented meibomian area of loss of grade 2. Results suggest that pre-corneal lipid layers and meibomian glands may prevent loss and evaporation of aqueous layer in brachycephalic breeds.

 

Keywords: surface, eye, lipid, aqueous, ophthalmology.


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