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OJVRTM

 

Online Journal of Veterinary Research©

(Including Medical and Laboratory Research)

Established 1994

ISSN 1328-925X

 

Volume 28 (8): 473-480, 2024.

Effects of Glycyrrhiza glabra on wound healing in Sprague-Dawley male rats.

 

Aboutorab Tabatabaei Naeini, Ahmad Oryan, Behrooz Nikahval, Mahvash Toosinezhad.

 

School of Veterinary Medicine, Shiraz University Iran.

 

ABSTRACT

 

Naein  AT, Oryan A, Nikahval B, Toosinezhad M., Effects of Glycyrrhiza glabra on wound healing in Sprague-Dawley male rats, Onl J Vet Res., 28 (8): 473-480, 2024. Groups of 10 male Sprague-Dawley rats were subjected to dorsal skin wounds under anaesthesia treated with or without (controls) Glycyrrhiza glabra powder daily for 5 days. Wounds were rinsed daily by sterile saline solution. Healing was determined planimetrically on days 0, 5, 10, 15 and 20 for biomechanical properties and microscopy. We found no difference between treated and non-treated wounds but compared with normal skin had ~8 to ~10 fold reduced tension and strength. By microscopy we observed reduced inflammatory cells, enhanced fibroblasts and tissue alignment in rats treated Glycyrrhiza glabra powder.

 

Keywords: Licorice powder, Wound healing, Cutaneous, rat.

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