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Online Journal of Veterinary Research

(Including Medical and Laboratory Research)

Established 1994
ISSN 1328-925X


26 (9): 717-724, 2022.

Cytology of canine leproid granuloma in a Rottweiler.


Zahra Nikousefat1, Mohammad Hashemnia2*, Moosa Javdani3


Department of 1Clinical Sciences and 2Pathobiology, School of Veterinary Medicine, Razi University, Kermanshah, 3Department of Veterinary Surgery and Radiology, Faculty of Veterinary Medicine, Shahrekord University, Shahrekord, Iran




Nikousefat Z, Hashemnia M, Javdani M., Cytology of leprosy granuloma in a Rotweiler, Onl J Vet Res., (9): 717-724, 2022. A 3-year-old male Rottweiler with non-responsive multiple ulcerated and alopecic nodules on skin of face and back were aspirated for biopsies and microscopy. We observed numerous macrophages with variable lymphocytes, plasma cells and fewer neutrophils. Within macrophages we detected medium length bacilli. Histologically, the lesions were chiefly pyogranulomatous within the dermis. Pyogranulomas were composed chiefly of macrophages, epitheloid cells, neutrophils, and fewer lymphocytes or plasma cells and rare giant cells. A large number of acid-fast bacilli were found within the cytoplasm of many macrophages by Ziehl-Neelsen stain but could not be cultivated in vitro. A diagnosis of canine leproid granuloma was made based on findings.


Key words: Canine leproid granulomas, mycobacteria, pyogranulomas, acid fast bacilli.