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Online Journal of Veterinary Research

(Including Medical and Laboratory Research)

Established 1994

ISSN 1328-925X


Volume 28(6): 327-333, 2024.

Epidural buprenorphine with bupivacaine, xylazine or ketamine in dogs.


Sharma YK, Pandey SS, Pandey SK


Department of Veterinary Surgery and Radiology, College of Veterinary Science and Animal Health, Mpow, India.




Sharma YK, Pandey SS, Pandey SK, Epidural buprenorphine with bupivacaine, xylazine or ketamine in dogs, Onl J Vet Res., 28(6): 327-333, 2024. Six dogs were given 0.04 mg/kg IM atropine sulphate 20 min before epidural injection of 0.05 mg/kg buprenorphine with 1 mg/kg bupivacaine, 0.75 mg/kg xylazine and 3 mg/kg ketamine. Mean induction time was 2.40 0.15, 2.72 0.19 and 3.65 0.30 min respectively. There were no differences for onset of analgesia between bupivacaine and xylazine but ketamine delayed it ~34% (P<0.05). Ketamine prolonged anesthesia ~38% (P<0.05). Bupivacaine and xylazine reduced pulse and heart rates 15-17% whereas ketamine boosted them ~17% (P<0.05). Buvicaine, xylazine and ketamine reduced respiratory rates 42, 40 and 30% and rectal temperatures 3, 2 and 4% (P < 0.05).


Key-words: Epidural, buprenorphine, bupivacaine, xylazine, ketamine, dogs.