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OJVRTM
Online Journal of Veterinary Research©
Volume 15 (1): 93-97, 2011. Redacted 2017.
Effects of
intramuscular chlorpromazine on intraocular pressure in clinically
normal dogs
Selk Ghaffari M 1,
Hajikhani R1, Trbolova
A 2, Noormohammadi M 1
1-
Department of Clinical Sciences, School of Veterinary Medicine, Islamic Azad
University- Karaj Branch. Karaj, Iran. 2- Clinic of
Small Animals, University of Veterinary Medicine and Pharmacy, Kosice,
Slovakia.
ABSTRACT
Selk
Ghaffari M, Hajikhani R, Trbolova A, Noormohammadi M,
Effects of intramuscular chlorpromazine on intraocular pressure in clinically normal
dogs, Online J Vet Res, 15 (1): 93-97,
2011, Fifteen crossbreed dogs were randomly
assigned to a treatment or control group. Baseline intraocular pressure (IOP) values were recorded
just before administration of intramuscular chlorpromazine and placebo in both groups. The treatment group included
8 dogs that received intramuscular chlorpromazine (1 mg/kg). The control group included 7 dogs given intramuscular
saline solution (2 ml). IOP values were measured 15, 25, 60, and 120 minutes after chlorpromazine and saline administration in both groups. There were no significant differences
in IOP between the pretreatment and post-treatment values in both groups. In
conclusion, intramuscular chlorpromazine has no clinically significant effects
on IOP in the dog.
Key words:
chlorpromazine, intraocular
pressure (IOP), dog
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