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OJVRTM
Online Journal of Veterinary Research
©
Volume 14 (2): 311-315, 2010. Redacted 2017.
Effects of topical 1% tropicamide
on intraocular pressure in clinically normal guinea pigs
Selk Ghaffari M, Farhodi F
Department of Clinical Sciences, School of Veterinary
Medicine, Islamic Azad, University-Karaj Branch. Karaj- Iran
ABSTRACT
Selk Ghaffari M, Farhodi F Effects of topical 1% tropicamide
on intraocular pressure in clinically normal guinea pigs Online J Vet Res., 14 (2): 311-315, 2010. Groups of 8
guinea pigs were given 1% tropicamide ophthalmic
drops in a randomly chosen eye and the
opposite eye served as the untreated controls. Controls included eight guinea pigs given a drop of artificial tear solution in a randomly
chosen eye and the contralateral eye received no drug. Intraocular
pressure readings were obtained immediately before and at 30, 60, 90 and 120
min after drug administration in both treatment and control groups. Mean IOP was not significantly altered in any eye at any
time point during the study period compared with baseline in both groups.
In Conclusion, topical application of 1%
tropicamide had no statistically significant effect
on intraocular pressure in guinea pigs.
Key words: guinea pigs, 1% tropicamide, intraocular
pressure, applanation tonometery .
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