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OJVRTM
Online Journal of Veterinary
Research©
Volume 16 (3):232-239, 2012. Extensively Redacted
2017.
Effect of experimental bursal disease infection in
chickens on humoral responses to a challenge with avian influenza virus subtype
H9N2.
Motamed N DVM1, Mayahi
M DVM PhD2, Seifi MR DVM PhD.3
12 Poultry Research Center and 3Department of Pathobiology,
School of Veterinary Medicine, Shahid chamran University, Ahvaz, Iran.
ABSTRACT
Motamed N, Mayahi M, Seifi
MR, Effect of experimental bursal disease infection in chickens on humoral responses
to a challenge with avian influenza virus subtype H9N2. Onl
J Vet Res, 16 (3):232-239, 2012. One day old chicks were infected via
intranasal and intraocular routes with 103 CID50 bursal virus (IBDV), and at 30 days with 106 EID50 avian
influenza virus (AIV) H9N2. Another group was infected with AIV only and
controls were not infected. Sera was tested for AIV
antibody by hem-agglutination inhibition test (HI). Symptoms and mortality was
enhanced in birds infected with both viruses. Infection by IBD suppressed H9N2
antibody in birds with both viruses. Birds shed virus from trachea and cloaca
for longer periods in birds infected by both viruses. A previous history of
IBDV infection in chickens may induce susceptibility to avian influenza virus
infection and pathology by LPAI viruses.
Key words: Infectious bursal disease, Avian influenza, Virus shedding, broiler chickens
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