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Online Journal of Veterinary Research©
Volume 22 (3):247-252, 2018.
Clinical signs and pathology in 24 horses poisoned by zinc phosphide.
Moaddab H¹, Siavosh Haghighi ZM²*, Tavanaeimanesh H.³
1-Department of clinical Sciences, 2- Basic Sciences and Pathobiology, Faculty of Veterinary Medicine, Razi University, Kermanshah, 3- Department of Internal Medicine, Faculty of Veterinary Medicine, University of Tehran, Iran *Corresponding author mailing address: Minoosh.Siavosh@gmail.com
Moaddab H, Siavosh ZM, Tavanaeimanesh H., Clinical signs and pathology in 24 horses poisoned by zinc phosphide, Onl J Vet Res., 22 (3):247-252, 2018. Zinc phosphide is a grey crystalline powder used as a rodenticide. Under wet or acidic conditions zinc phosphide degrades into phosphine gas. We describe clinical findings and pathology in 24 horses during 4 outbreaks of Zinc Phosphide poisoning over a period of 16 years. All horses exhibited profuse sweating, 18 had convulsions, 13 showed colic and 21 were recumbent. All horses had tachycardia, tremor, pyrexia, whereas 22 had tachypnea, 19 suffered from weakness, 14 showed ataxia and 15 with altered mentation. Blood tests revealed 17 horses were hypoglycemic, 19 had elevated gamma glutamyl transferase, aspartate transaminase (21), alkaline phosphatase (22), creatinine (13) and 16, increased blood urea nitrogen (BUN). Postmortem changes included widespread petechia, ecchymoses and vascular congestion, hepatic lipidosis, pulmonary edema and necrosis in cerebral cortex. In this study, treatment with activated charcoal mixed with magnesium hydroxide or sodium bicarbonate, fluid therapy or phenobarbital were ineffective and all horses eventually died. According to this survey the prognosis of horses poisoned with zinc phosphide is poor.
Key words: Horse, zinc phosphide, rodenticide poisoning.