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OJVRTM
Online Journal of
Veterinary Research©
Volume
22 (2): 99-103, 2018.
Effect
of two hour halothane anesthesia on blood cell counts and serum biochemical
values in sheep and calves.
Rajaian H., DVM, PhD; Nazifi S., DVM, PhD;
Nayyeri K., DVM; Saberi Afshar F., DVM and Ehteshami F.,
DVM.
School of
Veterinary Medicine, Shiraz University, Shiraz, Iran
ABSTRACT
Rajaian H, Nazifi S, Nayyeri K, Saberi Afshar F, Ehteshami F., Effect of
two hour halothane anesthesia on blood cell counts and serum biochemical values
in sheep and calves, Onl J Vet Res., 22 (2): 99-103, 2018. Anesthesia was
induced and maintained 2 hours by halothane in 5 sheep and 4 calves by closed circuit
anesthetic machine. Average induction time was ~5 minutes in both groups. White
blood cell count, packed cell volumes (PCV) blood urea nitrogen and serum
glucose, cholesterol, total protein, protein fractions, creatine
phosphokinase, alanine and aspartate transaminases, sodium and potassium were determined.
Liver biopsies were taken two weeks after anesthesia10, 11 and were
examined for any pathological changes using light microscopy. In sheep, blood PCV
increased 1 and 7 days after induction and neutrophils by 2 hours whereas
cholesterol declined 1-2 hrs. Pre-anesthetic serum cholesterol level was ~3
times greater in calves compared with sheep. There were no significant changes
in any parameter in calves. Liver biopsies taken from sheep or calves 2 weeks
after anesthesia did not indicate abnormalities and we found no prominent
alterations in other biochemical parameters during or after anesthesia.
Key words: Anesthesia, Halothane, Sheep, Calves,
Clinical pathology.
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