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OJVRTM

Online Journal of Veterinary Research© 

Volume 19(8): 480-485, 2015

 

Khodakaram-Tafti A1, Asasi K2, Keshtkar N1, Zarei F1

 

Departments of Pathology1 and  Clinical Studies2, School of Veterinary Medicine, Shiraz University, Shiraz, Iran,

 

ABSTRACT

 

Khodakaram-Tafti A, Asasi K, Keshtkar N, Zarei F., Effect of furazolidone on testis of adult Japanese quail (Coturnix coturnix japonica), Onl J Vet Res., 19(8): 480-485, 2015. Furazolidone is used to prevent or treat bacterial and protozoal diseases in humans and animals. Furazolidone was administered to 3 groups of 20 quails each with feed, at doses of 400, 800 and 1200 mg/kg daily for 14 days.  Controls (20) were given feed only. Various degrees of degenerative changes and atrophy of testes were observed grossly and microscopically after 7 and 14 days and compared with controls. In those given 800 and 1200 mg/kg and killed after 7days, testes appeared enlarged and pale whereas in those slaughtered at 2wks showed  atrophy. In quails given 400mg/kg only mild congestion and swelling was seen. Microscopically compared with controls, quails given 800 or 1200 mg/kg furazolidone showed atrophied seminiferous tubules with mild to severe lesions. In those given 400mg/kg tubules appeared normal but smaller with fewer spermatozoids compared with controls These preliminary findings need to be confirmed by demonstration of individual microscopic images from all quails

 

Key words: pathology, testis, furazolidone, infertility, adult Japanese quail.

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