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OJVR

 

Online Journal of Veterinary Research©

 

 Volume 14 (1):87-95, 2010. Redacted 2017.


Phylogenetic relationship between foot-and-mouth disease virus serotype ‘A’ isolates and vaccine strains.

 

Amit Kumar Verma1#, Mahima2, B.C. Pal3, S. K. Yadav4, Amit Kumar5 and Malik Raies6

 

Department of Epidemiology and Veterinary Preventive Medicine, Pandit Deen Dayal Upadhaya Pashu Chikitsa Vigyan Vishwa Vidhyalaya evam Gau Anusandhan Sansthan, Mathura – 281001, India $Part of PhD. Thesis submitted to DUVASU, Mathura, India. 1 PhD, corresponding author & Assistant Professor E mail: amitvet1@yahoo.co.in, dr_amitverma@sify.com 2 MVSc, Veterinary officer. State Veterinary Hospital, Heempur Deepa, Bijnor, UP 3 PhD, Ex Professor and Head and Scientist Emeritus4 PhD, Professor and Incharge 5 MVSc, Assistant Professor. Department of Microbiology and Immunology.6 MVSc


ABSTRACT

 

Verma AK, Mahima, Pal BC, Yadav SK, Kumar A, Raies M. Phylogenetic relationships between foot-and-mouth disease virus serotype ‘A’ isolates and vaccine strains, Online J Vet Res. 14 (1):87-95, 2010. Partial nucleotide sequence of the capsid polypeptide coding gene 1D (VP1-encoding) gene of three foot-and-mouth disease (FMD) serotype A virus isolates recovered from recent different outbreaks in India were determined. These sequences were compared with each other and those from previously occurred outbreaks in India including two vaccine virus strains sequences. On the basis of phylogenetic analysis the recent viruses could be grouped into genotype VII and are divergent from the vaccine strains. This work provides valuable insights into the epidemiological situation of FMDV type A in India and necessary information in the selection of suitable vaccine strain(s), if required, for the National FMD control program.

 

KEYWORDS: Foot-and-mouth disease virus, Serotype A, Genetic analysis, Phylogenetic analysis.


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