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OJVR
Online Journal of
Veterinary Research
Volume 10 (2) : 102 -107, 2006. Extensively redacted 2018.
Subacute
effects of lindane on Clarias
gariepinus.
Alo OS1, Abatan MO2.
1Department of Animal Production and Health, University
of ADO EKITI, 2 Department of Veterinary Pharmacology, University of
Ibadan, Nigeria.
ABSTRACT
Alo OS, Abatan MO, Subacute effects of lindane on Clarias gariepinus, Onl J
Vet Res., 10 (2) : 102 -107, 2006. Effects of 80 parts per
billion subacute lindane for 14 days on six Claris gariepinus
fish are described. Six controls were not exposed to Lindane.
Fish exposed to Lindane lost weight from 326 ± 7 ±
18.2 to 280.0 ± 9.3 grams by 14 days. In fish exposed to lindane,
mean + SEM packed cell volume was 14.8 ± 2.9 but in controls 25.0 ±
2.7%, and in same order Hemoglobin 4.8 ± 2.4 and 8.4
± 2.4 mg/dl, white blood cells 5580 ± 732.9 and 18150 ± 573.4 103/CM3,
red blood cell count 2.57 ± 1.4 and 4.4 ± 0.89 106/UC and mean
corpuscular haemoglobin (MCHC) 31.7 ± 5.8 and 33.39 ± 2.64 g/dl,
respectively. Serum alanine phosphatase
in fish exposed was 91 ± 13.74 and
controls 6.50 ± 14.69 IU/L, aspartame transaminase 730 ± 110.06 and 450 ±
205.20 IU/L and alanine transaminase 67.50 ± 13.73 and 41.00 ± 16.32 IU/L. All
values from fish exposed to Lindane, except MCHC were
significantly different (P < 0.05) from same control values. Results suggest
that Clarias gariepinus
exposed to subacute lindane exhibited marked
anorexia, reduced packed cell volumes anemia,
weakness and leucopenia. Histopathology revealed
marked inflammatory cell infiltration. The study suggested that lindane even in low doses is very toxic to Claris gariepinus and
its presence in Nigerian water resources affects fresh water fish.
KEY-WORDS Lindane, fish, toxicity
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