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Online Journal of Veterinary Research©
Volume 22 (3):267-272, 2018.
Epidural effects of buprenorphine with bupivacaine, xylazine and ketamine in dogs
Sharma YK, Pandey SS, Pandey SK
Department of Veterinary Surgery and Radiology, College of Veterinary Science and Animal Health, Mpow, India.
Sharma YK, Pandey SS, Pandey SK, Epidural effects of buprenorphine with bupivacaine, xylazine and ketamine in dogs, Onl J Vet Res., 22 (4) : 267-272, 2018. Six dogs were given atropine sulphate 0.04 mg/kg IM 20 min before treatments with (I) buprenorphine hydrochloride 0.05 mg/kg and bupivacaine hydrochloride 0.5% 1 mg/kg, (II) buprenorphine hydrochloride 0.05 mg/kg and xylazine hydrochloride 0.75 mg/kg b.wt and (III), buprenorphine hydrochloride 0.05 mg/kg with ketamine hydrochloride 3 mg/kg epidurally at the lumbosacral space. The mean induction time was 2.40 ± 0.15, 2.72 ± 0.19 and 3.65 ± 0.30 min for treatments I, II and III respectively. There was no significant variation between onset values of analgesia in treatment I and II, but treatment III differed significantly (P<0.05) from I and II. Average duration of analgesia for treatments I, II and III was 70.93 ± 3.92, 88.44 ± 2.70 and 112.68 ± 3.40 min, respectively, and again, treatment III differed significantly (P<0.05) from I and II. Significant decreases in pulse, heart and respiration rates occurred in treatments I and II whereas in III, they increased. Body temperatures decreased significantly during all treatments.
Key-words: Epidural, buprenorphine, bupivacaine, xylazine, ketamine, dogs.