©2020-2032. All Rights Reserved. Online Journal of Veterinary Research. You may not store these pages in any form except for your own personal use. All other usage or distribution is illegal under international copyright treaties. Permission to use any of these pages in any other way besides the before mentioned must be gained in writing from the publisher. This article is exclusively copyrighted in its entirety to OJVR. This article may be copied once but may not be, reproduced or re-transmitted without the express permission of the editors. This journal satisfies the refereeing requirements (DEST) for the Higher Education Research Data Collection (Australia). Linking: To link to this page or any pages linking to this page you must link directly to this page only here rather than put up your own page.
Online Journal of Veterinary Research©
Volume 24 (6):356-365, 2020.
Histopathology and F1L gene sequence analysis of contagious ecthyma virus in sheep and goats.
Davari SA1 (DVM, PhD), Sayyari M2* (DVM, PhD), Mohammadi A2 (DVM, PhD)
1Department(s) of Pathobiology, Faculties of Veterinary Medicine, Zabol University, Zabol, 2Shiraz University, Shiraz, Iran
Davari SA, Sayyari M, Mohammadi A., Histopathology and F1L gene sequence analysis of contagious ecthyma virus in sheep and goats, Onl J Vet Res., 24 (6):356-365, 2020. Contagious ecthyma, also known as Orf, is a common viral skin disease of sheep and goats caused by Parapoxvirus. We describe pathology and Orf virus F1L gene sequence by PCR from sheep and goats. Tissue samples revealed epidermal hyperplasia with prominent rete ridges, hydropic degeneration of the necrotic keratinocytes, eosinophilic intracytoplasmic inclusion bodies in vacuolated cells and subcorneal pustules. By PCR we found ~50% positive to the virus of which 10 were sequenced for Orf-059-Shiraz strain recorded in GeneBank for phylogenetic analysis and suggested that this gene is highly conserved.
Key words: Contagious ecthyma, Histopathology, Molecular analysis.