©2021-2032
All Rights Reserved. Online
Journal of Veterinary Research. You may not store
these pages in any form except for your own personal use. All other usage or
distribution is illegal under international copyright treaties. Permission to use
any of these pages in any other way besides the before mentioned must be gained
in writing from the publisher. This
article is exclusively copyrighted in its entirety to onlinejournals@gmail.com
publications. This article may be copied once but may not be, reproduced or re-transmitted without the express permission of the
editors. Linking: To link to this page or any pages
linking to this page you must link directly to this page only here rather than
put up your own page.
OJVRTM
Online Journal of Veterinary Research©
Volume 25(2): 104-109, 2021.
GC dispersion in
non-coding RNAs from E.coli K12 genome.
Sridhar J,
Rafi ZA.
Centre of Excellence in Bioinformatics,
School of Biotechnology, Madurai Kamaraj University,
Madurai 625021, India.
ABSTRACT
Sridhar J, Rafi ZA GC dispersion in non-coding RNAs from E. coli K12 genome. Onl J Vet Res., 25(2): 104-109, 2021. Non-coding RNAs (ncRNAs)
are primary transcripts which exert their function directly in the cell instead
of coding for amino acids. The GC distribution of ncRNAs
in the entire E.coli K12 genome
(RNome) was analyzed. GC distribution in coding genes
was illustrated with tRNA, rRNA,
sRNA and intergenic regions. Results showed that 83% of sRNAs
GC distribution ranged from 45% to 52%. A shift in GC content of tRNA genes decoding polar-charged (non-hydrophobic) and
hydrophobic amino acids and a correlation between the GC distribution and tRNA iso-types was found. This
study suggests that tRNA iso-types
having low GC% may decode non-hydrophobic amino acids and high GC%, hydrophobic
ones.
Key words: %GC, ncRNA, GC bias, hash value, sRNA.
FULL-TEXT (SUBSCRIBE OR PURCHASE TITLE)