1996-2021. All Rights Reserved. Online Journal of Veterinary Research. You may not store these pages in any form except for your own personal use. All other usage or distribution is illegal under international copyright treaties. Permission to use any of these pages in any other way besides the before mentioned must be gained in writing from the publisher. This article is exclusively copyrighted in its entirety to OJVR. This article may be copied once but may not be, reproduced or re-transmitted without the express permission of the editors. This journal satisfies the refereeing requirements (DEST) for the Higher Education Research Data Collection (Australia). Linking: To link to this page or any pages linking to this page you must link directly to this page only here rather than put up your own page


OJVRTM

Online Journal of Veterinary Research

 

Volume 23 (10):1007-1016, 2019.


Sutureless amniotic membrane 2-Octyl cyanoacrylate patch for treatment of corneal alkali burn in dogs.

 

Abbaszadeh M1, Aldavood SJ1, Foroutan A.R2, Azizzadeh M3, Izadi SS1, Selk Ghaffari M4.

1Department of Clinical Sciences, Faculty of Veterinary Medicine, University of Tehran. 2Department of Clinical Sciences, Eye Research Center, Iran university of Medical Sciences, Tehran. 3Department of Clinical Sciences, Faculty of Veterinary Medicine, Ferdowsi University, Mashhad. 4Department of Clinical Sciences, Faculty of Veterinary Medicine, Islamic Azad University-Karaj Branch, Karaj, Iran. Work was completed at internal medicine research center, Department of Clinical Sciences, University of Tehran, Iran and was not supported by any grant.

 

ABSTRACT

 

Abbaszadeh M, Aldavood SJ, Foroutan AR, Azizzadeh M, Izadi SS, Selk Ghaffari M., Sutureless amniotic membrane 2-Octyl cyanoacrylate patch for treatment of corneal alkali burn in dogs, Onl J Vet Res., Volume 23 (10):1007-1016, 2019. Authors describe surgery and clinical outcomes of a tissue adhesive 2-Octyl cyanoacrylate (Dermabond) amniotic membrane patch for treatment of experimental corneal burn in dogs. Alkali wounds were inflicted on the central corneas of dogs under anesthesia by applying a round filter paper, 6.0 mm diameter, soaked in 1 N NaOH for 60 sec unilaterally on each eye. Three groups of 5 dogs each were uncovered controls (1), covered by amniotic membrane with amniotic cell membrane sutured to cornea with 100 nylon (2), or covered with amniotic membrane with 2-Octyl cyanoacrylate (3). Operating time, clinical outcome, epithelial defects, opacity, blepharospasm, membrane retention, vascularization and ocular discharges were monitored 21 days. Surgery time in dogs treated with adhesive membrane was less than those sutured (P<0.001). Membrane persisted longer (P < 0.023) and cornea healed faster with adhesive (P = 0.038). However, we found no differences with corneal opacity or blepharospasm. Ocular discharges were also less in dogs treated with adhesive membrane and none of the corneas stained.

 

Key words: Dog, Amniotic membrane, 2-Octyl cyanoacrylate, Dermabond, corneal alkali burn.


MAIN

 

FULL-TEXT (SUBSCRIBE OR PURCHASE TITLE)