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OJVRTM
Online Journal of Veterinary Research©
(Including Medical and Laboratory Research)
Established 1994
ISSN 1328-925X
Volume 27 (7): 447-450, 2023.
Analgesic and anti-inflammatory effects of Phoenix dactylifera
in Wistar rats
Zainab M Albermani, Saadia
Saleh Mehdy Zeiny, Mohammad
Taha Naqi, Shatha Mousa Mlaghee Al Safi.
Faculty of Veterinary Medicine, University of Kufa, Iraq.
ABSTRACT
Albermani ZM,
Mehdy Zeiny
SS, Naqi MT, Mlaghee Al Safi SM., Analgesic and
anti-inflammatory effects of Phoenix dactylifera in Wistar rats, Onl J Vet Res., 27 (7): 447-450, 2023.
Authors report effect of 100 to 300mg/kg oral methanolic extract of Phoenix
dactylifera dates on analgesia and inflammation
in 7 groups of male and female Wistar rats. Controls
were given normal saline or Mobic. For the pain test, rats were injected intraperitoneally
with acetic acid 30 minutes before extract. For the inflammation test, rats
were given extract 30 minutes before formalin paw test. Contractions and paw
tests were evaluated every 5-20 minutes for 50 minutes. At doses of 200, 250
and 300 mg/kg extract we recorded no clinical signs whereas at 100-150mg/kg we
recorded abdominal contractions or hind limb stretches and paw redness up to 30
minutes. Compared with Mobic controls, results suggest >200mg/kg extract may
have suppressed pain and inflammation in Wistar rats.
Keywords: Phoenix dactylifera, analgesic, anti-inflammatory, rat.
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