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Online Journal of Veterinary Research

(Including Medical and Laboratory Research)

Established 1994

ISSN 1328-925X


Volume 27 (4): 228-232, 2023.

Effects of Spirulina platensis on enzymes induced by cyanide in Cyprinus carpio.


Mehrzad MehrabianFarda, Davar Shahsavania, Hasan Baghshanib, Hosna GholipourKananic


aDepartment of Food Hygiene and Aquaculture, bBasic Sciences, School of Veterinary Medicine, Ferdowsi University of Mashhad, cDepartment of fisheries, school of agriculture, Gonbad kavous University, Gonbad, Iran




Fard MM, Shahsavani D, Baghshani H, Kanani HG., Effects of Spirulina platensis on enzymes induced by cyanide in Cyprinus carpio, Onl J Vet Res., 27 (4): 228-232, 2023. We evaluate effect of cyanide and Spirulina platensis on liver, kidney, brain and gill alanine (ALT), aspartate (AST) transaminases, lactate dehydrogenase (LDH), alkaline phosphatase (ALP) and rhodanese in carp fish. Groups of 10 fish each were exposed to 0.4 ppm potassium cyanide with or without 10% dietary Spirulina platensis for 30 days. Results were compared against 10 untreated controls. In fish exposed to cyanide with or without spirulina platensis liver ALT increased (P < 0.001) 46-51% with no differences in kidney, brain or gill levels whereas liver AST increased (P < 0.05) 35-42% but in brain, Spirulina platensis supplement reduced (P < 0.05) AST levels 17% with no effect on other tisssues. Kidney LDH increased ~18% with or without supplement. We found no effect on ALP or rhodanese levels.


Keywords: Cyanide, Spirulina, Tissue enzyme, Cyprinus carpio