Volume 23 (6):516-521, 2019.
Effect of Cucurbita maxima seed extract on In vitro viability of
eggs, larvae and worms of Haemonchus contortus.
Ahmed N Abed Salih and Ali H Saliem
College of Veterinary Medicine, University of Baghdad, Iraq
Abed Salih AN, Saliem AH., Effect of Cucurbita maxima seed extract on In vitro viability of eggs, larvae and worms of Haemonchus contortus, Onl J Vet Res., 23 (6):516-521, 2019. We report dose dependent activity of Cucurbita maxima seed extract on in Vitro survival of Haemonchus contortus eggs, larvae and adult worms at doses of 50, 100 and 200mg/ml. Results were compared against non-treated water controls and 25mg/ml Albendazole. CM had no effect at 50mg/ml. At 100mg/ml egg hatching was inhibited ~19% and larvae ~9% but CM had no effect on adult worms. With 200mg/ml hatching, larvae and worms were inhibited 30.6, 15.9 and 7.7%. For albendazole the same values were ~95, 87 and 80%. We find that Cucurbita maxima seed extract had good dose-concentration correlation but poor effect against all stages of Haemonchus contortus in vitro compared with a standard anti-helminth.
Key words: Cucurbita maxima, gastrointestinal worms, anti-helminthes. Raw data provided after references.