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Online Journal of Veterinary Research

(Including Medical and Laboratory Research)

Established 1994

ISSN 1328-925X

Volume 26 (3): 202-212, 2022.

Plasma copper, zinc, manganese, selenium and antioxidant enzymes in

grazing pregnant ewes during dry season.


M Mohebbi-Fania, A Mirzaeib, S Nazifib, MR Tabandehc, Z Shabbooeid


a Department of Animal Health Management, b Department of Clinical Studies, School of Veterinary Medicine, Shiraz University, Shiraz 71345-1731, Iran; c Department of Basic Sciences, School of Veterinary Medicine, Shahid Chamran University, Ahvaz, Iran; d DVM student, School of Veterinary Medicine, Shiraz University, Shiraz, Iran




Mohebbi-Fani M, Mirzaei A, Nazifi S, Tabandeh MR, Shabbooei Z., Plasma copper, zinc, manganese, selenium and antioxidant enzymes in grazing pregnant ewes during dry season, Onl J Vet Res., 26 (3): 202-212, 2022. Plasma copper (Cu), zinc (Zn), manganese (Mn), selenium (Se) and erythrocyte malondialdehyde (MDA), superoxide dismutase (SOD) and glutathione peroxidase (GPX) were determined in 47 pregnant fat tailed ewes at 1st day of 51-day breeding before pregnancy and 120 days later at 70-120 days of pregnancy. Pregnancy was confirmed in 43 ewes by plasma progesterone at day 120. Ewes were grazed on medium-to-low quality pastures and cereal stubble given ~1 kg 40% alfalfa hay, 60% wheat straw with ~100g barley grain head/day. A trace mineralized supplement was available ad libitum. choice. Compared with values before pregnancy plasma copper declined (P < 0.01) 58% and Zinc 53% whereas selenium increased 79% and manganese 50%. Malondialdehyde increased (P < 0.001) 76%, whereas superoxide dismutase declined 29% and gluthathione peroxidase 32%. Increased metabolism during pregnancy along together with poor nutrition could be underlying findings. Fat tailed ewes may experience oxidative stress during pregnancy when they are mainly fed medium to low quality forages.


Key words: Copper, Zinc, Selenium, Superoxide dismutase, Glutathione peroxidase, Oxidative stress, Sheep.